High content screening identifies monensin as an EMT-selective cytotoxic compound

Epithelial-to-mesenchymal transition (EMT) is implicated in cancer metastasis and drug resistance. Specifically targeting cancer cells in an EMT-like state may have therapeutic value. In this study, we developed a cell imaging-based high-content screening protocol to identify EMT-selective cytotoxic...

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Detalles Bibliográficos
Autores principales: Vanneste, Marion, Huang, Qin, Li, Mengshi, Moose, Devon, Zhao, Lei, Stamnes, Mark A., Schultz, Michael, Wu, Meng, Henry, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361972/
https://www.ncbi.nlm.nih.gov/pubmed/30718715
http://dx.doi.org/10.1038/s41598-018-38019-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361972/
https://www.ncbi.nlm.nih.gov/pubmed/30718715
http://dx.doi.org/10.1038/s41598-018-38019-y

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