Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity

Antimicrobial peptides (AMPs) are a potential source of new molecules to counter the increase in antimicrobial resistant infections but a better understanding of their properties is required to understand their native function and for effective translation as therapeutics. Details of the mechanism o...

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Detalles Bibliográficos
Autores principales: Manzo, Giorgia, Ferguson, Philip M., Gustilo, V. Benjamin, Hind, Charlotte K., Clifford, Melanie, Bui, Tam T., Drake, Alex F., Atkinson, R. Andrew, Sutton, J. Mark, Batoni, Giovanna, Lorenz, Christian D., Phoenix, David A., Mason, A. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362004/
https://www.ncbi.nlm.nih.gov/pubmed/30718667
http://dx.doi.org/10.1038/s41598-018-37630-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362004/
https://www.ncbi.nlm.nih.gov/pubmed/30718667
http://dx.doi.org/10.1038/s41598-018-37630-3

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