Label-free Quantitative Analysis of Protein Expression Alterations in miR-26a-Knockout HeLa Cells using SWATH-MS Technology

MicroRNAs (miRNAs) bind to the 3ʹ-untranslated region of target mRNAs in a sequence-specific manner and subsequently repress gene translation. Human miR-26a has been studied extensively, but the target transcripts are far from complete. We first employed the CRISPR-Cas9 system to generate an miR-26a...

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Detalles Bibliográficos
Autores principales: Shen, Hexiao, Li, Li, Teng, Zhaowei, Meng, Tianqing, Kong, Xiangbin, Hu, Yan, Zhu, Yun, Ma, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362012/
https://www.ncbi.nlm.nih.gov/pubmed/30718521
http://dx.doi.org/10.1038/s41598-018-34904-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362012/
https://www.ncbi.nlm.nih.gov/pubmed/30718521
http://dx.doi.org/10.1038/s41598-018-34904-8

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