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Caveolin-1α regulates primary cilium length by controlling RhoA GTPase activity

The primary cilium is a single non-motile protrusion of the plasma membrane of most types of mammalian cell. The structure, length and function of the primary cilium must be tightly controlled because their dysfunction is associated with disease. Caveolin 1 (Cav1), which is best known as a component...

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Detalles Bibliográficos
Autores principales: Rangel, Laura, Bernabé-Rubio, Miguel, Fernández-Barrera, Jaime, Casares-Arias, Javier, Millán, Jaime, Alonso, Miguel A., Correas, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362014/
https://www.ncbi.nlm.nih.gov/pubmed/30718762
http://dx.doi.org/10.1038/s41598-018-38020-5