Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins

Sample fixation by vitrification is critical for the optimal structural preservation of biomolecules and subsequent high-resolution imaging by cryo-correlative light and electron microscopy (cryoCLEM). There is a large resolution gap between cryo fluorescence microscopy (cryoFLM), ~400-nm, and the s...

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Detalles Bibliográficos
Autores principales: Tuijtel, Maarten W., Koster, Abraham J., Jakobs, Stefan, Faas, Frank G. A., Sharp, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362030/
https://www.ncbi.nlm.nih.gov/pubmed/30718653
http://dx.doi.org/10.1038/s41598-018-37728-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362030/
https://www.ncbi.nlm.nih.gov/pubmed/30718653
http://dx.doi.org/10.1038/s41598-018-37728-8

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