Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2

Retinal ganglion cells (RGCs) undergo rapid cell death by apoptosis after injury but can be rescued by suppression of caspase-2 (CASP2) using an siRNA to CASP2 (siCASP2). Pigment epithelium-derived factor (PEDF), has neuroprotective and anti-angiogenic functions and protects RGC from death. The purp...

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Detalles Bibliográficos
Autores principales: Vigneswara, Vasanthy, Ahmed, Zubair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362048/
https://www.ncbi.nlm.nih.gov/pubmed/30718480
http://dx.doi.org/10.1038/s41419-019-1379-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362048/
https://www.ncbi.nlm.nih.gov/pubmed/30718480
http://dx.doi.org/10.1038/s41419-019-1379-6

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