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CYTL1 regulates bone homeostasis in mice by modulating osteogenesis of mesenchymal stem cells and osteoclastogenesis of bone marrow-derived macrophages

We previously showed that mice with knockout of Cytl1, a functionally uncharacterized cytokine candidate, exhibit normal endochondral ossification and long-bone development. Here, we investigated the potential functions of CYTL1 in bone homeostasis. We found that Cytl1(−/−) mice exhibited higher bon...

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Detalles Bibliográficos
Autores principales: Shin, Youngnim, Won, Yoonkyung, Yang, Jeong-In, Chun, Jang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362050/
https://www.ncbi.nlm.nih.gov/pubmed/30718470
http://dx.doi.org/10.1038/s41419-018-1284-4