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GPER activation protects against epithelial barrier disruption by Staphylococcusaureus α-toxin

Sex bias in innate defense against Staphylococcus aureus skin and soft tissue infection (SSTI) is dependent on both estrogen production by the host and S. aureus secretion of the virulence factor, α-hemolysin (Hla). The impact of estrogen signaling on the immune system is most often studied in terms...

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Detalles Bibliográficos
Autores principales: Triplett, Kathleen D., Pokhrel, Srijana, Castleman, Moriah J., Daly, Seth M., Elmore, Bradley O., Joyner, Jason A., Sharma, Geetanjali, Herbert, Guy, Campen, Matthew J., Hathaway, Helen J., Prossnitz, Eric R., Hall, Pamela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362070/
https://www.ncbi.nlm.nih.gov/pubmed/30718654
http://dx.doi.org/10.1038/s41598-018-37951-3