Unfolded protein response is an early, non-critical event during hepatic stellate cell activation

Hepatic stellate cells activate upon liver injury and help at restoring damaged tissue by producing extracellular matrix proteins. A drastic increase in matrix proteins results in liver fibrosis and we hypothesize that this sudden increase leads to accumulation of proteins in the endoplasmic reticul...

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Detalles Bibliográficos
Autores principales: Mannaerts, Inge, Thoen, Lien F. R., Eysackers, Nathalie, Cubero, Francisco Javier, Batista Leite, Sofia, Coldham, Iain, Colle, Isabelle, Trautwein, Christian, van Grunsven, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362073/
https://www.ncbi.nlm.nih.gov/pubmed/30718473
http://dx.doi.org/10.1038/s41419-019-1327-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362073/
https://www.ncbi.nlm.nih.gov/pubmed/30718473
http://dx.doi.org/10.1038/s41419-019-1327-5

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