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Ser46 phosphorylation of p53 is an essential event in prolyl-isomerase Pin1-mediated p53-independent apoptosis in response to heat stress

Heat stroke has increased in frequency worldwide in recent years and continues to have a high morbidity and mortality. Identification of the mechanisms mediating heat stoke is important and necessary. Our preliminary study revealed heat stress (HS)-induced apoptosis of vascular endothelial cells was...

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Detalles Bibliográficos
Autores principales: Li, Li, Su, Zijun, Zou, Zhimin, Tan, Hongping, Cai, Daozhang, Su, Lei, Gu, Zhengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362080/
https://www.ncbi.nlm.nih.gov/pubmed/30718466
http://dx.doi.org/10.1038/s41419-019-1316-8