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The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication

In order to evaluate the influence of CDK5 inhibitory peptide (CIP) on Human alphaherpesvirus 1 (HSV-1) replication, we constructed two recombinant adeno-associated-virus 2 (rAAV2) vectors encoding CIP fused with cyan-fluorescent-protein (CFP), with or without nuclear localization signal. A third ve...

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Detalles Bibliográficos
Autores principales: Man, Adrian, Slevin, Mark, Petcu, Eugen, Fraefel, Cornel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362106/
https://www.ncbi.nlm.nih.gov/pubmed/30718749
http://dx.doi.org/10.1038/s41598-018-37989-3