SmvA is an important efflux pump for cationic biocides in Klebsiella pneumoniae and other Enterobacteriaceae

The multidrug resistant (MDR) opportunistic pathogen Klebsiella pneumoniae has previously been shown to adapt to chlorhexidine by increasing expression of the MFS efflux pump smvA. Here we show that loss of the regulator SmvR, through adaptation to chlorhexidine, results in increased resistance to a...

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Detalles Bibliográficos
Autores principales: Wand, Matthew E., Jamshidi, Shirin, Bock, Lucy J., Rahman, Khondaker Miraz, Sutton, J. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362122/
https://www.ncbi.nlm.nih.gov/pubmed/30718598
http://dx.doi.org/10.1038/s41598-018-37730-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362122/
https://www.ncbi.nlm.nih.gov/pubmed/30718598
http://dx.doi.org/10.1038/s41598-018-37730-0

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