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SmvA is an important efflux pump for cationic biocides in Klebsiella pneumoniae and other Enterobacteriaceae
The multidrug resistant (MDR) opportunistic pathogen Klebsiella pneumoniae has previously been shown to adapt to chlorhexidine by increasing expression of the MFS efflux pump smvA. Here we show that loss of the regulator SmvR, through adaptation to chlorhexidine, results in increased resistance to a...
Autores principales: | Wand, Matthew E., Jamshidi, Shirin, Bock, Lucy J., Rahman, Khondaker Miraz, Sutton, J. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362122/ https://www.ncbi.nlm.nih.gov/pubmed/30718598 http://dx.doi.org/10.1038/s41598-018-37730-0 |
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