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Dissolution and bioavailability improvement of bioactive apigenin using solid dispersions prepared by different techniques

Apigenin (APG) is a poorly soluble bioactive compound/nutraceutical which shows poor bioavailability upon oral administration. Hence, the objective of this research work was to develop APG solid dispersions (SDs) using different techniques with the expectation to obtain improvement in its in vitro d...

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Detalles Bibliográficos
Autores principales: Alshehri, Sultan M., Shakeel, Faiyaz, Ibrahim, Mohamed A., Elzayat, Ehab M., Altamimi, Mohammad, Mohsin, Kazi, Almeanazel, Osaid T., Alkholief, Musaed, Alshetaili, Abdullah, Alsulays, Bader, Alanazi, Fars K., Alsarra, Ibrahim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362180/
https://www.ncbi.nlm.nih.gov/pubmed/30766439
http://dx.doi.org/10.1016/j.jsps.2018.11.008