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Chemerin reverses neurological impairments and ameliorates neuronal apoptosis through ChemR23/CAMKK2/AMPK pathway in neonatal hypoxic–ischemic encephalopathy

Hypoxic–ischemic encephalopathy (HIE) is a devastating neurological event that contributes to the prolonged neurodevelopmental consequences in infants. Therapeutic strategies focused on attenuating neuronal apoptosis in the penumbra appears to be promising. Given the increasingly recognized neuropro...

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Detalles Bibliográficos
Autores principales: Zhang, Yixin, Xu, Ningbo, Ding, Yan, Doycheva, Desislava Met, Zhang, Yiting, Li, Qian, Flores, Jerry, Haghighiabyaneh, Mina, Tang, Jiping, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362229/
https://www.ncbi.nlm.nih.gov/pubmed/30718467
http://dx.doi.org/10.1038/s41419-019-1374-y