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Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts
Vascularization and efficient perfusion are long-standing challenges in cardiac tissue engineering. Here we report engineered perfusable microvascular constructs, wherein human embryonic stem cell-derived endothelial cells (hESC-ECs) are seeded both into patterned microchannels and the surrounding c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362250/ https://www.ncbi.nlm.nih.gov/pubmed/30718840 http://dx.doi.org/10.1038/s41467-019-08388-7 |