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Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts

Vascularization and efficient perfusion are long-standing challenges in cardiac tissue engineering. Here we report engineered perfusable microvascular constructs, wherein human embryonic stem cell-derived endothelial cells (hESC-ECs) are seeded both into patterned microchannels and the surrounding c...

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Detalles Bibliográficos
Autores principales: Redd, Meredith A., Zeinstra, Nicole, Qin, Wan, Wei, Wei, Martinson, Amy, Wang, Yuliang, Wang, Ruikang K., Murry, Charles E., Zheng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362250/
https://www.ncbi.nlm.nih.gov/pubmed/30718840
http://dx.doi.org/10.1038/s41467-019-08388-7