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A cell-free platform for the prenylation of natural products and application to cannabinoid production

Prenylation of natural compounds adds structural diversity, alters biological activity, and enhances therapeutic potential. Because prenylated compounds often have a low natural abundance, alternative production methods are needed. Metabolic engineering enables natural product biosynthesis from inex...

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Detalles Bibliográficos
Autores principales: Valliere, Meaghan A., Korman, Tyler P., Woodall, Nicholas B., Khitrov, Gregory A., Taylor, Robert E., Baker, David, Bowie, James U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362252/
https://www.ncbi.nlm.nih.gov/pubmed/30718485
http://dx.doi.org/10.1038/s41467-019-08448-y