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A cell-free platform for the prenylation of natural products and application to cannabinoid production
Prenylation of natural compounds adds structural diversity, alters biological activity, and enhances therapeutic potential. Because prenylated compounds often have a low natural abundance, alternative production methods are needed. Metabolic engineering enables natural product biosynthesis from inex...
Autores principales: | Valliere, Meaghan A., Korman, Tyler P., Woodall, Nicholas B., Khitrov, Gregory A., Taylor, Robert E., Baker, David, Bowie, James U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362252/ https://www.ncbi.nlm.nih.gov/pubmed/30718485 http://dx.doi.org/10.1038/s41467-019-08448-y |
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