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Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan

Pharmacometabolomics has been already successfully used in toxicity prediction for one specific adverse effect. However in clinical practice, two or more different toxicities are always accompanied with each other, which puts forward new challenges for pharmacometabolomics. Gastrointestinal toxicity...

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Detalles Bibliográficos
Autores principales: Gao, Yiqiao, Li, Wei, Chen, Jiaqing, Wang, Xu, Lv, Yingtong, Huang, Yin, Zhang, Zunjian, Xu, Fengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362258/
https://www.ncbi.nlm.nih.gov/pubmed/30766787
http://dx.doi.org/10.1016/j.apsb.2018.09.006