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Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan
Pharmacometabolomics has been already successfully used in toxicity prediction for one specific adverse effect. However in clinical practice, two or more different toxicities are always accompanied with each other, which puts forward new challenges for pharmacometabolomics. Gastrointestinal toxicity...
Autores principales: | Gao, Yiqiao, Li, Wei, Chen, Jiaqing, Wang, Xu, Lv, Yingtong, Huang, Yin, Zhang, Zunjian, Xu, Fengguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362258/ https://www.ncbi.nlm.nih.gov/pubmed/30766787 http://dx.doi.org/10.1016/j.apsb.2018.09.006 |
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