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Is There a Positive Side to T Cell Exhaustion?

T cell “exhaustion” describes a state of late-stage differentiation usually associated with active prevention of functionality via ligation of negative signaling receptors on the cell surface, and which can be reversed by blocking these interactions. This contrasts with T cell “senescence,” which ha...

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Detalles Bibliográficos
Autor principal: Pawelec, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362299/
https://www.ncbi.nlm.nih.gov/pubmed/30761152
http://dx.doi.org/10.3389/fimmu.2019.00111