Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund–Thomson syndrome

RecQ-like helicase 4 (RECQL4) is mutated in patients suffering from the Rothmund–Thomson syndrome, a genetic disease characterized by premature aging, skeletal malformations, and high cancer susceptibility. Known roles of RECQL4 in DNA replication and repair provide a possible explanation of chromos...

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Detalles Bibliográficos
Autores principales: Yokoyama, Hideki, Moreno-Andres, Daniel, Astrinidis, Susanne A, Hao, Yuqing, Weberruss, Marion, Schellhaus, Anna K, Lue, Hongqi, Haramoto, Yoshikazu, Gruss, Oliver J, Antonin, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362308/
https://www.ncbi.nlm.nih.gov/pubmed/30718377
http://dx.doi.org/10.26508/lsa.201800120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362308/
https://www.ncbi.nlm.nih.gov/pubmed/30718377
http://dx.doi.org/10.26508/lsa.201800120

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