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The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis

The eukaryotic endoplasmic reticulum (ER) membrane contains essential complexes that oversee protein biogenesis and lipid metabolism, impacting nearly all aspects of cell physiology. The ER membrane protein complex (EMC) is a newly described transmembrane domain (TMD) insertase linked with various p...

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Detalles Bibliográficos
Autores principales: Volkmar, Norbert, Thezenas, Maria-Laetitia, Louie, Sharon M., Juszkiewicz, Szymon, Nomura, Daniel K., Hegde, Ramanujan S., Kessler, Benedikt M., Christianson, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362398/
https://www.ncbi.nlm.nih.gov/pubmed/30578317
http://dx.doi.org/10.1242/jcs.223453