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The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis
The eukaryotic endoplasmic reticulum (ER) membrane contains essential complexes that oversee protein biogenesis and lipid metabolism, impacting nearly all aspects of cell physiology. The ER membrane protein complex (EMC) is a newly described transmembrane domain (TMD) insertase linked with various p...
Autores principales: | Volkmar, Norbert, Thezenas, Maria-Laetitia, Louie, Sharon M., Juszkiewicz, Szymon, Nomura, Daniel K., Hegde, Ramanujan S., Kessler, Benedikt M., Christianson, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362398/ https://www.ncbi.nlm.nih.gov/pubmed/30578317 http://dx.doi.org/10.1242/jcs.223453 |
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