Ethyl Pyruvate Modulates Murine Dendritic Cell Activation and Survival Through Their Immunometabolism

Attenuating the innate immunity activation could ameliorate inflammation and disease in settings such as transplant rejection or autoimmunity. Recently, a pivotal role for metabolic re-programming in TLR-induced dendritic cell (DC) activation has emerged. Ethyl pyruvate (EP), a pyruvate derivative,...

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Detalles Bibliográficos
Autores principales: Chakhtoura, Marita, Chain, Robert W., Sato, Priscila Y., Qiu, Connie C., Lee, Michael H., Meissler, Joseph J., Eisenstein, Toby K., Koch, Walter J., Caricchio, Roberto, Gallucci, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362406/
https://www.ncbi.nlm.nih.gov/pubmed/30761126
http://dx.doi.org/10.3389/fimmu.2019.00030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362406/
https://www.ncbi.nlm.nih.gov/pubmed/30761126
http://dx.doi.org/10.3389/fimmu.2019.00030

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