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A comparative evaluation of hybrid error correction methods for error-prone long reads

BACKGROUND: Third-generation sequencing technologies have advanced the progress of the biological research by generating reads that are substantially longer than second-generation sequencing technologies. However, their notorious high error rate impedes straightforward data analysis and limits their...

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Detalles Bibliográficos
Autores principales: Fu, Shuhua, Wang, Anqi, Au, Kin Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362602/
https://www.ncbi.nlm.nih.gov/pubmed/30717772
http://dx.doi.org/10.1186/s13059-018-1605-z