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Sulforaphane Attenuates H(2)O(2)-induced Oxidant Stress in Human Trabecular Meshwork Cells (HTMCs) via the Phosphatidylinositol 3-Kinase (PI3K)/Serine/Threonine Kinase (Akt)-Mediated Factor-E2-Related Factor 2 (Nrf2) Signaling Activation

BACKGROUND: The aim of this study was to investigate whether and how sulforaphane (SFN), a novel promising nuclear factor-E2-related factor 2 (Nrf2) activator, exerted antioxidative stress through activating Nrf2 signaling. MATERIAL/METHODS: Cultured human trabecular meshwork cells (HTMCs) were trea...

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Detalles Bibliográficos
Autores principales: Liu, Yuzhen, Liu, Pan, Wang, Qiang, Sun, Fengmei, Liu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362759/
https://www.ncbi.nlm.nih.gov/pubmed/30689624
http://dx.doi.org/10.12659/MSM.913849