Afadin cooperates with Claudin-2 to promote breast cancer metastasis

Claudin-2 promotes breast cancer liver metastasis by enabling seeding and early cancer cell survival. We now demonstrate that the PDZ-binding motif of Claudin-2 is necessary for anchorage-independent growth of cancer cells and is required for liver metastasis. Several PDZ domain-containing proteins...

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Detalles Bibliográficos
Autores principales: Tabariès, Sébastien, McNulty, Alexander, Ouellet, Véronique, Annis, Matthew G., Dessureault, Mireille, Vinette, Maude, Hachem, Yasmina, Lavoie, Brennan, Omeroglu, Atilla, Simon, Hans-Georg, Walsh, Logan A., Kimbung, Siker, Hedenfalk, Ingrid, Siegel, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362814/
https://www.ncbi.nlm.nih.gov/pubmed/30692208
http://dx.doi.org/10.1101/gad.319194.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362814/
https://www.ncbi.nlm.nih.gov/pubmed/30692208
http://dx.doi.org/10.1101/gad.319194.118

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