CD44 splice isoform switching determines breast cancer stem cell state

Although changes in alternative splicing have been observed in cancer, their functional contributions still remain largely unclear. Here we report that splice isoforms of the cancer stem cell (CSC) marker CD44 exhibit strikingly opposite functions in breast cancer. Bioinformatic annotation in patien...

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Detalles Bibliográficos
Autores principales: Zhang, Honghong, Brown, Rhonda L., Wei, Yong, Zhao, Pu, Liu, Sali, Liu, Xuan, Deng, Yu, Hu, Xiaohui, Zhang, Jing, Gao, Xin D., Kang, Yibin, Mercurio, Arthur M., Goel, Hira Lal, Cheng, Chonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362815/
https://www.ncbi.nlm.nih.gov/pubmed/30692202
http://dx.doi.org/10.1101/gad.319889.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362815/
https://www.ncbi.nlm.nih.gov/pubmed/30692202
http://dx.doi.org/10.1101/gad.319889.118

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