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Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program

The molecular regulation of zygotic genome activation (ZGA) in mammals remains an exciting area of research. Primed mouse embryonic stem cells contain a rare subset of “2C-like” cells that are epigenetically and transcriptionally similar to the two-cell embryo and thus represent an in vitro approxim...

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Detalles Bibliográficos
Autores principales: Eckersley-Maslin, Mélanie, Alda-Catalinas, Celia, Blotenburg, Marloes, Kreibich, Elisa, Krueger, Christel, Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362816/
https://www.ncbi.nlm.nih.gov/pubmed/30692203
http://dx.doi.org/10.1101/gad.321174.118