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Amorphous aggregation of tau in the presence of titanium dioxide nanoparticles: biophysical, computational, and cellular studies

BACKGROUND: Nanoparticles (NPs) when injected into the body can reach target tissues like nervous system and interact with tau proteins and neurons. This can trigger conformational changes of tau and may affect NP toxicity. METHODS: In this study, we used several biophysical techniques (extrinsic an...

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Detalles Bibliográficos
Autores principales: Fardanesh, Aida, Zibaie, Sedigheh, Shariati, Behdad, Attar, Farnoosh, Rouhollah, Fatemeh, Akhtari, Keivan, Shahpasand, Koroosh, Saboury, Ali Akbar, Falahati, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362919/
https://www.ncbi.nlm.nih.gov/pubmed/30774341
http://dx.doi.org/10.2147/IJN.S194658