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ZNF433 positively regulates the beta-catenin/ TCF pathway in prostate cancer and enhances the tumorigenicity of cancer cells

BACKGROUND: Prostate cancer often shows the over-activation of beta-catenin/t-cell factor (TCF) signaling. It remains largely unknown how the beta-catenin/TCF transcriptional machinery is tightly controlled. METHODS: The ZNF433 mRNA and protein levels in the clinical tissues were examined using q-PC...

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Detalles Bibliográficos
Autores principales: Gu, Shuo, Hou, Peijin, Liu, Kun, Niu, Xiaobing, Wei, Bingjian, Mao, Fei, Xu, Zongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362961/
https://www.ncbi.nlm.nih.gov/pubmed/30774387
http://dx.doi.org/10.2147/OTT.S178150