SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition

Upregulation of the PI3K pathway has been implicated in the initiation and progression of several types of cancer, including renal cell carcinoma (RCC). Although several targeted therapies have been developed for RCC, durable and complete responses are exceptional. Thus, advanced RCC remains a letha...

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Detalles Bibliográficos
Autores principales: Terzo, Esteban A., Lim, Aaron R., Chytil, Anna, Chiang, Yun Chen, Farmer, Leah, Gessner, Kathryn H., Walker, Cheryl Lyn, Jansen, Valerie M., Rathmell, W. Kimryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363018/
https://www.ncbi.nlm.nih.gov/pubmed/30774762
http://dx.doi.org/10.18632/oncotarget.26567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363018/
https://www.ncbi.nlm.nih.gov/pubmed/30774762
http://dx.doi.org/10.18632/oncotarget.26567

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