Cargando…

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors

Melanoma is one of the fastest growing cancers in the United States and is accompanied with a poor prognosis owing to tumors being resistant to most therapies. Atypical protein kinase Cs (aPKC) are involved in malignancy in many cancers. We previously reported that aPKCs play a key role in melanoma&...

Descripción completa

Detalles Bibliográficos
Autores principales: Ratnayake, Wishrawana S., Apostolatos, Christopher A., Apostolatos, André H., Schutte, Ryan J., Huynh, Monica A., Ostrov, David A., Acevedo-Duncan, Mildred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363030/
https://www.ncbi.nlm.nih.gov/pubmed/29781749
http://dx.doi.org/10.1080/19336918.2018.1471323