Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion

Myeloid cell leukemia-1 (MCL-1), closely related to B-cell lymphoma 2 (BCL-2), has a well-established role in cell survival and has emerged as an important target for cancer therapeutics. We have demonstrated that inhibiting MCL-1 is efficacious in suppressing tumour progression in pre-clinical mode...

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Detalles Bibliográficos
Autores principales: Young, Adelaide IJ, Timpson, Paul, Gallego-Ortega, David, Ormandy, Christopher J., Oakes, Samantha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Commentary - Solicited
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363037/
https://www.ncbi.nlm.nih.gov/pubmed/29166822
http://dx.doi.org/10.1080/19336918.2017.1393591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363037/
https://www.ncbi.nlm.nih.gov/pubmed/29166822
http://dx.doi.org/10.1080/19336918.2017.1393591

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