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Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion
Myeloid cell leukemia-1 (MCL-1), closely related to B-cell lymphoma 2 (BCL-2), has a well-established role in cell survival and has emerged as an important target for cancer therapeutics. We have demonstrated that inhibiting MCL-1 is efficacious in suppressing tumour progression in pre-clinical mode...
Autores principales: | Young, Adelaide IJ, Timpson, Paul, Gallego-Ortega, David, Ormandy, Christopher J., Oakes, Samantha R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363037/ https://www.ncbi.nlm.nih.gov/pubmed/29166822 http://dx.doi.org/10.1080/19336918.2017.1393591 |
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