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Open Source Pharmacokinetic/Pharmacodynamic Framework: Tutorial on the BioGears Engine

BioGears is an open‐source, lumped parameter, full‐body human physiology engine. Its purpose is to provide realistic and comprehensive simulations for medical training, research, and education. BioGears incorporates a physiologically based pharmacokinetic/pharmacodynamic (PK/PD) model that is design...

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Detalles Bibliográficos
Autores principales: McDaniel, Matthew, Carter, Jennifer, Keller, Jonathan M, White, Steven A., Baird, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363067/
https://www.ncbi.nlm.nih.gov/pubmed/30411537
http://dx.doi.org/10.1002/psp4.12371