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Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids

Disruption of intestinal barrier homeostasis is an important pathogenic factor in conditions such as irritable bowel syndrome (IBS). Lactobacillus rhamnosus GG (LGG) improves IBS symptoms through unclear mechanisms. Previous studies utilizing colorectal adenocarcinoma cell lines showed that LGG meta...

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Detalles Bibliográficos
Autores principales: Han, Xu, Lee, Allen, Huang, Sha, Gao, Jun, Spence, Jason R., Owyang, Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363076/
https://www.ncbi.nlm.nih.gov/pubmed/30040527
http://dx.doi.org/10.1080/19490976.2018.1479625