Handling Missing Dosing History in Population Pharmacokinetic Modeling: An Extension to MDM Method

A major challenge in population pharmacokinetic modeling is handling data with missing or potentially incorrect dosing records. Leaving such records untreated or “commented out” will cause bias in parameter estimates. Several approaches were previously developed to address this challenge. Published...

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Detalles Bibliográficos
Autores principales: Wang, Yuhuan, Liu, Xiaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363138/
https://www.ncbi.nlm.nih.gov/pubmed/30536631
http://dx.doi.org/10.1002/psp4.12374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363138/
https://www.ncbi.nlm.nih.gov/pubmed/30536631
http://dx.doi.org/10.1002/psp4.12374

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