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Handling Missing Dosing History in Population Pharmacokinetic Modeling: An Extension to MDM Method
A major challenge in population pharmacokinetic modeling is handling data with missing or potentially incorrect dosing records. Leaving such records untreated or “commented out” will cause bias in parameter estimates. Several approaches were previously developed to address this challenge. Published...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363138/ https://www.ncbi.nlm.nih.gov/pubmed/30536631 http://dx.doi.org/10.1002/psp4.12374 |