Production of recombinant TSA-1 and evaluation of its potential for the immuno-therapeutic control of Trypanosoma cruzi infection in mice

A therapeutic vaccine for human Chagas disease (American trypanosomiasis caused by Trypanosoma cruzi) is under development based on the success of vaccinating mice with DNA constructs expressing the antigens Tc24 and Tc-TSA-1. However, because DNA and nucleic acid vaccines produce less than optimal...

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Detalles Bibliográficos
Autores principales: de la Cruz, Juan Jose, Villanueva-Lizama, Liliana, Dzul-Huchim, Victor, Ramírez-Sierra, María-Jesus, Martinez-Vega, Pedro, Rosado-Vallado, Miguel, Ortega-Lopez, Jaime, Flores-Pucheta, Claudia Ivonne, Gillespie, Portia, Zhan, Bin, Bottazzi, Maria Elena, Hotez, Peter J., Dumonteil, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363145/
https://www.ncbi.nlm.nih.gov/pubmed/30192702
http://dx.doi.org/10.1080/21645515.2018.1520581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363145/
https://www.ncbi.nlm.nih.gov/pubmed/30192702
http://dx.doi.org/10.1080/21645515.2018.1520581

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