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Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli
Osteoarthritis (OA) is a degenerative condition caused by dysregulation of multiple molecular signalling pathways. Such dysregulation results in damage to cartilage, a smooth and protective tissue that enables low friction articulation of synovial joints. Matrix metalloproteinases (MMPs), especially...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363221/ https://www.ncbi.nlm.nih.gov/pubmed/30677026 http://dx.doi.org/10.1371/journal.pcbi.1006685 |