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Multi-study inference of regulatory networks for more accurate models of gene regulation

Gene regulatory networks are composed of sub-networks that are often shared across biological processes, cell-types, and organisms. Leveraging multiple sources of information, such as publicly available gene expression datasets, could therefore be helpful when learning a network of interest. Integra...

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Detalles Bibliográficos
Autores principales: Castro, Dayanne M., de Veaux, Nicholas R., Miraldi, Emily R., Bonneau, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363223/
https://www.ncbi.nlm.nih.gov/pubmed/30677040
http://dx.doi.org/10.1371/journal.pcbi.1006591