The Human Cytomegalovirus U(L)38 protein drives mTOR-independent metabolic flux reprogramming by inhibiting TSC2

Human Cytomegalovirus (HCMV) infection induces several metabolic activities that are essential for viral replication. Despite the important role that this metabolic modulation plays during infection, the viral mechanisms involved are largely unclear. We find that the HCMV U(L)38 protein is responsib...

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Detalles Bibliográficos
Autores principales: Rodríguez-Sánchez, Irene, Schafer, Xenia L., Monaghan, Morgan, Munger, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363234/
https://www.ncbi.nlm.nih.gov/pubmed/30677091
http://dx.doi.org/10.1371/journal.ppat.1007569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363234/
https://www.ncbi.nlm.nih.gov/pubmed/30677091
http://dx.doi.org/10.1371/journal.ppat.1007569

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