Nephron progenitor commitment is a stochastic process influenced by cell migration

Progenitor self-renewal and differentiation is often regulated by spatially restricted cues within a tissue microenvironment. Here, we examine how progenitor cell migration impacts regionally induced commitment within the nephrogenic niche in mice. We identify a subset of cells that express Wnt4, an...

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Detalles Bibliográficos
Autores principales: Lawlor, Kynan T, Zappia, Luke, Lefevre, James, Park, Joo-Seop, Hamilton, Nicholas A, Oshlack, Alicia, Little, Melissa H, Combes, Alexander N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363379/
https://www.ncbi.nlm.nih.gov/pubmed/30676318
http://dx.doi.org/10.7554/eLife.41156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363379/
https://www.ncbi.nlm.nih.gov/pubmed/30676318
http://dx.doi.org/10.7554/eLife.41156

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