scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling

Loss of sensory hair cells leads to deafness and balance deficiencies. In contrast to mammalian hair cells, zebrafish ear and lateral line hair cells regenerate from poorly characterized support cells. Equally ill-defined is the gene regulatory network underlying the progression of support cells to...

Descripción completa

Detalles Bibliográficos
Autores principales: Lush, Mark E, Diaz, Daniel C, Koenecke, Nina, Baek, Sungmin, Boldt, Helena, St Peter, Madeleine K, Gaitan-Escudero, Tatiana, Romero-Carvajal, Andres, Busch-Nentwich, Elisabeth M, Perera, Anoja G, Hall, Kathryn E, Peak, Allison, Haug, Jeffrey S, Piotrowski, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363392/
https://www.ncbi.nlm.nih.gov/pubmed/30681411
http://dx.doi.org/10.7554/eLife.44431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363392/
https://www.ncbi.nlm.nih.gov/pubmed/30681411
http://dx.doi.org/10.7554/eLife.44431

Ejemplares similares