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Stimulation of Retinal Pigment Epithelium With an α7 nAChR Agonist Leads to Müller Glia Dependent Neurogenesis in the Adult Mammalian Retina

PURPOSE: The adult mammalian retina is typically incapable of regeneration when damaged by disease or trauma. Restoration of function would require generation of new adult neurons, something that until recently, mammals were thought to be incapable of doing. However, previous studies from this labor...

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Detalles Bibliográficos
Autores principales: Webster, Mark K., Barnett, Betty J., Stanchfield, Megan L., Paris, Joshua R., Webster, Sarah E., Cooley-Themm, Cynthia A., Levine, Edward M., Otteson, Deborah C., Linn, Cindy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363405/
https://www.ncbi.nlm.nih.gov/pubmed/30721274
http://dx.doi.org/10.1167/iovs.18-25722