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Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion
Upon fusion of the secretory granule with the plasma membrane, small molecules are discharged through the immediately formed narrow fusion pore, but protein discharge awaits pore expansion. Recently, fusion pore expansion was found to be regulated by tissue plasminogen activator (tPA), a protein pre...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363410/ https://www.ncbi.nlm.nih.gov/pubmed/30504267 http://dx.doi.org/10.1085/jgp.201812182 |