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Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening
One of the major factors known to cause neuronal hyperexcitability is malfunction of the potassium channels formed by KCNQ2 and KCNQ3. These channel subunits underlie the M current, which regulates neuronal excitability. Here, I investigate the molecular mechanisms by which epilepsy-associated mutat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363412/ https://www.ncbi.nlm.nih.gov/pubmed/30578330 http://dx.doi.org/10.1085/jgp.201812221 |