A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel

The swelling-activated anion channel VRAC has fascinated and frustrated physiologists since it was first described in 1988. Multiple laboratories have defined VRAC’s biophysical properties and have shown that it plays a central role in cell volume regulation and possibly other fundamental physiologi...

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Detalles Bibliográficos
Autores principales: Strange, Kevin, Yamada, Toshiki, Denton, Jerod S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363415/
https://www.ncbi.nlm.nih.gov/pubmed/30651298
http://dx.doi.org/10.1085/jgp.201812138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363415/
https://www.ncbi.nlm.nih.gov/pubmed/30651298
http://dx.doi.org/10.1085/jgp.201812138

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